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127 Another clinical trial in 50 patients with tinnitus, half of whom also had hearing loss, found treatment with intramuscular injections providing 100 mg vitamin B1, 100 mg vitamin B6, and 1,000 mcg vitamin B12 twice weekly led to tinnitus improvement mainly in those without hearing loss

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the sites discussion of whether TB-500 is a promising therapy for chronic inflammatory conditions applies the same preclinical-versus-clinical caution used here

427,428,429 The compound NLY01 is particularly effective at attenuating the activity of proinflammatory microglia and preventing the transformation of astrocytes to a reactive phenotype