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Another potential therapeutic, Minocycline is a microglial inhibitor which reduces BBB dysfunction by preventing production of glutamate, matrix metalloproteinases, and the proinflammatory cytokine, IL-1, and increasing the levels of cells responsible for the remyelination of neurons which would be relevant in treating AD [138, 140,141,142]

Specifically, a review of clinical trials on the use of BPC-157 has characterized it as safe both in treating inflammatory bowel disease and wound healing, noting that no events of toxicity had been reported throughout those trials.

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