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Methods Yeast strains and plasmids The yeast strains used in this study include the wild-type Saccharomyces cerevisiae EG103 ( MAT leu2-3 112 his31 trp1-289a ura3-52 GAL + ) and the MnSOD-deficient yeast strain EG110 ( EG103 sod2 :: TRP1 ), kindly provided by Edith Gralla, University of California, Los Angeles and Valeria C

MCAS and histamine intolerance require careful history, trigger review, medication review, diet context, and sometimes laboratory evaluation or specialist collaboration

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