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The shift towards H 2 S-producing pathways may be driven by down-regulation of the aerobic oxidative degradation of cysteine to taurine, mediated by cysteine dioxygenase, as evidenced by the lower taurine/cysteine ratio in arterial cord blood, not only in severe IPTB cases, irrespective of treatment, but in NAC-treated moderate IPTB cases as well

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10.3390/toxins7030846 41 CarpenaM.Nuez-EstevezB.Soria-LopezA.Simal-GandaraJ

Evidence from experimental studies forms the basis of administration of glutathione for absorption from orobuccal mucosa as mentioned in the previous section