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In case the study is on humans, the sample size must be calculated to achieve a statistical power of at least 80% [473]

It uses nicotinamide adenine dinucleotide phosphate (NADPH) to restore glutathione to its active form

In some embodiments, the lipid-based drug delivery formulation or composition comprises a water-soluble preservative wherein the preservative is a benzethonium salt (e.g., benzethonium chloride), benzoic acid, and/or a benzylkonium salt (e.g., benzylkonium chloride)

[1] [4] The safety of glutathione injection in patients with severe hepatic or renal impairment has not been established, and its use in these populations should be carefully considered and monitored by a healthcare provider