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[3] Various B vitamins act as cofactors for methylation, including B2 and B12

Jardim-Messeder D, Zamocky M, Sachetto-Martins G, Margis-Pinheiro M (2022) Chloroplastic ascorbate peroxidases targeted to stroma or thylakoid membrane: the chicken or egg dilemma

It is predominantly localized in peroxisomes, into which catalase monomers are imported where heme addition and tetramer formation occur (Lazarow and de Duve 1973)