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It is a small synthetic molecule that blocks an enzyme called NNMT (nicotinamide N-methyltransferase)

PL BioScience has advanced an oral BPC-157 formulation (designated PL-10) to Phase II clinical trials for inflammatory bowel disease representing the most clinically advanced human development of oral BPC-157 to date.3 Human peer-reviewed results from these trials are pending, but the preclinical rationale is strong

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[3] The therapeutic window depends entirely on getting the ratio of GCGR-to-GLP-1R activity right too much glucagon signaling relative to GLP-1 could worsen glucose control