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Experimental evidence using a high-iron diet demonstrated that increased iron levels favored Tfh and GCB cell expansion, enhanced secretion of inflammatory cytokines IFN- and IL-17A by CD4 + T cells, promoted autoantibody production in MRL/lpr lupus mice, and worsened their disease phenotype

Active cancer or history of malignancy Pregnancy or breastfeeding Known peptide allergies Athletes subject to anti-doping testing (WADA prohibited) Raynauds disease or phenomenon Cold urticaria (hives from cold) Uncontrolled hypertension Peripheral vascular disease Open wounds (for local application) Pregnancy Cardiovascular conditions Diabetes (especially with neuropathy) Current infections Immunosuppression Blood clotting disorders Quality control issues represent perhaps the greatest practical risk with BPC-157

Your practitioner will recommend the most appropriate method

, 2009, 26, (DOI: 10.1007/s11095-009-9939-6) 5 E A Neuwelt et al , Nat