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For a 1.6 mg target dose: Volume to Draw = Desired DoseConcentration = 1.6 mg4 mg/mL = 0.4 mL Convert to syringe units

*Correspondence: Masao Miyazaki, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Together, these results suggest that SLC25A45 deletion leads to a shift in fuel choice toward carbohydrates/glucose catabolism due to a reduced systemic carnitine pool and impaired long-chain fatty acid oxidation, while SLC25A45 KO mitochondria can utilize alternative fuels, such as pyruvate and medium-chain fatty acids

A5 Projected number of people with Alzheimer's dementia, 20202060: This figure comes from the CHAP study