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In some instances, bimodal formulations allow for a constant rate of release of an immediate release component (multiparticulate agent (e.g., micronized active agent)) and a constant rate of release of an extended release component (e.g., an encapsulated active agent that serves as a depot for extending the release of an active agent)

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While vitamin B12 can be obtained from animal-based foods like meat, fish, eggs, and dairy products, some individuals may have difficulty absorbing it efficiently due to various factors such as age, gastrointestinal issues, or dietary restrictions

Optional maintenance: once initial goals are met, tapering dose or frequency, with periodic checkins to sustain benefits