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A 2022 study showed that, in the year 2019, the economic cost of smoking-related illness the costs of healthcare and lost productivity was almost 1.5-2.5% of the gross domestic product of Indonesia

These viruses are named after the crown-like appearance, which is attributed to a glycosylated cell surface spike (S) protein with two functional domains: S1 and S2 ( Upon exposure, the virus enters its host cell and targets the angiotensin converting receptors (ACE receptors) (Figure 1), which are predominantly present in alveolar cells ( Figure 1 While the pathogenesis of the infection caused by the virus is an area of intense investigation, evidence suggest that during SARS-CoV-2 infection there is an increase neutrophils which may contribute to severe respiratory disease with worse outcomes ( Kawasaki Disease and Emergence of MIS-C During the COVID-19 Pandemic Kawasaki disease (KD), described by Tomisaku Kawasaki (case series of 50 children in Japan) in 1967, is a systemic vasculitis in children and leading causes of childhood acquired heart disease ( MIS-C shares similarities to KD and toxic shock syndrome