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Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure: Increase in blood pressure, headache, nasal congestion, rhinitis, nosebleed, sore throat, cough, upper respiratory infections, nausea, flushing, and abdominal cramps

As previously mentioned, whenever ROS concentration in a stressed cell increases beyond its scavenging capacity, the cell encounters an oxidative phase, which leads to oxidative modification and cellular damage, which eventually progresses to cell death

It downregulates inflammatory mediators such as IL-6, indirectly modulating hepc activity and restoring iron homeostasis (87, 88)

Cellular reprogramming as a tool to model human aging in a dish