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Investigated for skin appearance proxies in preclinical and cosmetic-science contexts (texture, firmness, visible tone) without making therapeutic claims

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The peptide operates through multiple interconnected pathways rather than a single target, which accounts for its diverse benefits

The remaining medial layer was cut into small pieces, placed in Dulbecco's modified Eagle's medium (DMEM) containing 4.5 g/L glucose, 10 mmol/L sodium pyruvate, and 20% FBS supplemented with 100 U/mL of penicillin and 100 g/mL of streptomycin, and incubated at 37 C in a humidified atmosphere containing 5% CO 2