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Phase transitions of multivalent proteins can promote clustering of membrane receptors

The authors found distinct shifts of the microbiota composition in the large intestine alongside a pro-inflammatory response with increased CD3 + T-cell infiltration in the colonic tissue

The presence of an ordered R-domain position poses a surprise, since many alternate models exist for the R-domain mechanism that include a completely disordered R-domain or an R-domain that resides only between NBD1 and NBD2 in a semi-ordered state