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Nowadays we can understand that sex, age, race and ethnicity, in the context of socioeconomic status and lifestyle (tobacco, alcohol, education, physical exercise, unbalanced diet, etc.) impacts directly in its prevalence [7, 8, 10, 27 36]

Find out what a recent study showed in the Folate section of our B Vitamin Supplements Review, which includes our Top Picks for folate and other B vitamins

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Except for some unusual findings for lung cancer discussed below, associations between elevated serum B12 and increased disease or mortality are most plausibly explained by reverse causation, in which underlying disease raises B12 levels rather than elevated B12 causing disease