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They follow a clear physical pattern involving reduced oxygen, unstable blood vessels, and repeated nerve stimulation inside the brain

One possible explanation for this counterintuitive result is that, although the acute effect of high-frequency TMS is to increase excitability, the long-term effect of repeated stimulation could instead be suppressive

Researchers from the University of Arizona College of Medicine, the University of Illinois College of Medicine, the University of California-San Francisco and the University of Louisville School of Medicine also contributed to the study

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