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When protein antigen was not inhaled as an aerosolized solution, but rather administered through the intranasal route, environmental tobacco smoke exposure failed to trigger the antigen-specific immune response to inhaled antigens

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Our data show that between 1999 and 2022, smoking rates declined across almost all age groups, with a slight increase among the ages of 65-74, however the oldest population (aged 65-75 and older) consistently showing the lowest overall percentages