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The Role of Endothelial Dysfunction in Cardiovascular Disease At the core of most cardiovascular disease is endothelial dysfunction a breakdown in the integrity and function of the inner lining of blood vessels

Bone homeostasis, maintained by the balance between osteoclast-mediated bone resorption and osteoblast-mediated bone formation, is regulated by various signaling pathways such as receptor activator of nuclear factor-B ligand/receptor activator of nuclear factor-B/osteoprotegerin (RANKL/RANK/OPG), interleukin-1/tumor necrosis factor- (IL-1/TNF-), and Notch

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