Anxiety disorders include generalised anxiety (GAD), panic disorder (PD), social anxiety disorder (SAD), and post-traumatic stress disorder (PTSD) ( Studies have shown that -asarone isolated from the volatile oil of ATT can regulate the activity of hypothalamic Fcorticotrophin-releasing factor (CR), change the central norepinephrine system, prevent the decrease of BDNF (brain-derived neurotrophic factor), tropomyosin receptor kinase (TrkB) expression in the hippocampus (Lee et al., 2014), decreased BDNF and TrkB expression in the hippocampus is the cause for the development of anxiety
Cell 59 , 321332 (2015)
Aged garlic extract the only water-based garlic supplement showed a safe profile in toxicity studies and exhibited no undesirable side effects when combined with anticoagulants (warfarin), antiplatelets (aspirin), cholesterol-lowering (statins) drugs, or anticancer drugs (doxorubicin, 5-fluorouracil, methotrexate) in clinical settings (reviewed in 6)
doi: Seiwerth S, Brcic L, Vuletic L, et al
