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Many such compounds are supported mainly by preclinical findings or small-scale clinical studies of variable quality

Following spinal cord injury, zinc promotes the transfer of healthy mitochondria from microglia to injured neurons by regulating SIRT3-mediated Mfn2, thereby rescuing neuronal mitochondria, reducing oxidative stress, restoring ATP production, enhancing neuronal survival and improving motor recovery 155

Glutathione, which supports immunological function, may help protect the skin from external harm and create a more luminous complexion

In patients with eGFR below 30 mL/min, urinary concentrations are insufficient for antibacterial effect, the drug accumulates systemically, and peripheral neuropathy risk increases substantially