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219,220 The anti-inflammatory and immunomodulatory functions are mainly 14-ring and 15-ring

Additionally, peptide therapy may not be appropriate for individuals taking immunosuppressant medications or those dealing with active systemic infections, autoimmune disorders, or poorly controlled metabolic conditions

More than 1,100 marketed drugs are known to cause DILI worldwide, with the nonsteroidal anti-inflammatory drug acetaminophen (APAP) being the most extensively investigated