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Exceeding the stability period , after 1430 days, degradation products may accumulate

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The fibroblast populations that maintain mucosal connective tissue express the same collagen synthesis pathways, and SPARC and decorin upregulation data from Pickarts transcriptomic analyses covers targets common to fibroblast populations across tissue types (PMID: 25904764)

Korean J Radiol 24:224 Steinmetz JD, Culbreth GT, Haile LM et al (2023) Global, regional, and national burden of osteoarthritis, 19902020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021