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Absorption into the CNS after intranasal administration has been postulated to occur via the olfactory and trigeminal neuronal pathways (intraneuronal) and diffusion across mucosal barrier and olfactory plate (extraneuronal), depending on the size, polarity, and odorant nature

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A randomized, placebo-controlled clinical trial was conducted on 86 subjects aged 18 to 65 years, divided into two groups, one receiving ulva extract and the other receiving a placebo

In this context, early intervention with glutamate receptor blockade after noise exposure has been hypothesized to prevent excitotoxic injury to afferent synapses of inner hair cells