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26 and the references therein), they have limitations associated with well-known multiple adverse reactions, genotoxicity, and special requirements for storage, handling, and administration, posing challenges with respect to the standard operating procedure (SOP) for MDA campaigns requiring single or double dose activity, oral administration, minimal toxicity, and stability in tropical settings 27

Steroids decrease the production of inflammatory chemicals and reduce the sensitivity of nerve fibers to pain, generating fewer pain signals

Alternatively, hydrogenation, i.e., chemical reduction using metal catalysts, enables both saturation of remaining carbon-carbon double bonds and reduction of aldehydes to alcohols, thereby offering an efficient route for converting unsaturated aldehydes into saturated alcohols (Milone et al

Pandey VP, Singh S, Singh R, Dwivedi UN