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Central sensitization, chronic pain, and other symptoms: better understanding, better management

If you are concerned at all about methionine, AgelessRx recommends a short-term B12/MIC protocol

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However, no protection was evident when higher doses (600 mg/kg) were used74, again suggesting that in the face of sustained mitochondrial insult due to either higher doses or long-term exposure, alternate regulatory molecules are probably recruited to induce downstream features of the cell signaling cascade to ultimately result in hepatocyte necrosis