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Description

A phase I trial of PX-12, a small-molecule inhibitor of thioredoxin-1, administered as a 72-hour infusion every 21 days in patients with advanced cancers refractory to standard therapy

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This form of supplementation is beneficial and safe and can help treat a variety of symptoms while preventing damage to the body from the deficiency

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Key protective pathways include PI3K/Akt, Nrf2/ARE, MAPK, and NF-B

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W.ThronT.JanssenS.ShastriG

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