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Who Should Exercise Caution Pregnant and breastfeeding women should avoid berberine supplements, as there isn't sufficient research on safety during these periods

Iron levels influence macrophage polarization: low levels inhibit anti-inflammatory responses, while high levels promote them (Cornelissen et al., 2019)

Notably, while mouse iTregs can be highly suppressive in vivo , human iTregs generated under similar conditions often fail to acquire full regulatory function, highlighting important species-specific differences ( 2.2 The functional antagonism between Th17 cells and Treg cells The functional antagonism between Th17 cells and Treg cells primarily manifests in their reciprocal interactions and regulatory mechanisms within the immune system

Glutathione, often called the bodys master antioxidant, is a critical molecule involved in protecting cells from oxidative stress by neutralizing free radicals