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Uses DSIP is thought to increase sleep regulation, reduce motor activity to improve deep sleep, stimulate ACTH and LH levels, and reportedly normalize blood pressure

Combined use demonstrates improved outcomes in animal research, including: Faster formation of granulation tissue and wound closure Reduced edema and inflammation Enhanced tendon-to-bone integration and ligament tensile strength Systemic protection of organs such as liver and kidney in ischemia-reperfusion models Systematic reviews of over 35 preclinical studies consistently report positive histological and functional results, with no observed toxicity

These reactions are not regarded as a reason to stop steroid therapy, but patients should report their occurrence to their doctor

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