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Its amino-acid sequence showed a similarity of 80% compared with the porcine homolog and 69% with the bovine homolog (Figure 2)

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Here, we hypothesized that neuronal activation might maintain or trigger the astrocyte-to-neuron lactate shuttle (ANLS), whereby lactate is released from astrocytes to support the energy requirements of ATP-starved hypoxic neurons, and this leads to the observed neuroprotection

Ann Thorac Surg 100(5):1812-6, 2015