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This serious risk can be managed when an FDA-approved CBD drug product is taken under medical supervision, but it is less clear how it might be managed when CBD is used far more widely, without medical supervision, and not in accordance with FDA-approved labeling

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The tobacco plant, by its nature, contains nicotine from the time its a seedling to the end.[68] As a result, added Arcury, any task that requires the handling of tobacco in any form may expose workers to nicotine.[69] Nicotine may affect human health in distinct ways depending on how it enters the bodywhether absorbed through the skin, inhaled, or ingested.[70] Though the long-term effects of nicotine absorption through the skin are unknown, public health research on smoking indicates that nicotine exposure during childhood may have long-lasting consequences

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