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MSCs can increase serum IL-10 and IL-4 levels, while decreasing IL-17, IL-12, IL-6, TNF-, IFN- , and expression of HMGB-1 [117], which is consistent with clinical trial findings

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Long-term studies in laboratory models suggest that sustained NNMT inhibition may reprogram cellular metabolism toward enhanced oxidative capacity and improved stress resistance

Food Science and Technology , 40 (4), 972978