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Materials and methods Animals Wistar albino male rats (aged 12 weeks, 350400 g b.w.) were bred in-house (the animal facility at the Department of Pharmacology, School of Medicine, Zagreb, Croatia
Results showed a biphasic plasma concentrationtime profile, with an initial peak occurring within 24 h (initial absorption rate of 0.02 L/h) and a secondary sustained release phase (delayed absorption rate of 0.01 L/h) attributed to the gradual degradation of PLGA
A dual-trigger approach was employed, consisting of combined recombinant hCG (Ovidrel 250 g, Merck Serono S.p.A., Modugno, Italy) and a GnRH agonist (Lupro 2 mg, Nang Kuang Pharmaceutical Co., Ltd., Tainan, Taiwan), when at least one follicle reached a mean diameter of 18 mm
"The interaction of copper(II) and glycyl-L-histidyl-L-lysine, a growth-modulating tripeptide from plasma"
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