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If a med goes through your liver, its taxing it, so you need a liver-loving nutrient like NAC or glutathione. Cohen lists the following classes of medications that are known to deplete Glutathione2: Acid blockers Analgesics Antacids Antibiotics Antivirals Tricyclic antidepressants Excess Body Fat Excess body fat triggers overproduction of several damaging proteins known to cause oxidative stress

Barshtein G, Gural A, Arbell D, Barkan R, Livshits L, Pajic-Lijakovic I, et al

Their growing importance reflects increasing demand for compounds that support regenerative and recovery-focused research

Theres no strong scientific evidence linking oral glutathione to hormonal or kidney problems when taken at recommended doses