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Along with the beneficial effect noted with fundoscopy assessment, all BPC 157 rats (both g- and ng-regimen, those that received medication at 20 min after L-NAME, and those that received medication at 48 h after L-NAME) commonly presented preserved plexiform and inner nuclear layer and retinal thickness (Figure 6, Figure 7)

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740 Activity assays reveal that as expected, Zn II binding to site 2 inhibits turnover by QueD2, which suggests that the active site 1 may well be conformationally plastic or dynamically heterogeneous and must fold to accommodate substrate, in striking contrast to the housekeeping enzyme QueD