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In some cases, the dementia and other neurologic symptoms caused by vitamin B 12 deficiency can be reversed by vitamin treatment (42), but reversibility seems to be dependent upon the duration of the associated neurologic complications (41)

This is different from intradiscal injection, which requires medical guidance and imaging

However, in contrast to the tumour-suppressive effects described above, there is evidence that CDO1 can have a tumorigenic effect associated with aggressive glioblastoma, since its overexpression was detected in these tumours

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