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ten healthy volunteers taking zinc-carnosine (37.5 mg twice daily) were protected against the threefold increase in gastrointestinal permeability caused by indomethacin treatment (Mahmood 2007)

An extension of SPE is the use of online SPE, where the extraction column is part of the (U)HPLC-system and via valves connected to the main separation column(s)

J Pharmacol Exp Ther 1995;272:417422

In response to elevated serum levels of high-density lipoproteins (HDLP), calcium pangamate (CP) in patients with cerebrasthenic syndrome of atherosclerotic genesis allows a decrease in the cholesterol index of atherogenicity