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Due to the variety of experimental settings across these studies, the flavoring components, presence or absence of nicotine, human lifestyle issues (i.e., concomitant use of other products), and genetic variability, these studies may not strictly mimic real-life usage in humans

5 Effects may include: a rush feeling happy and excited changes in mood increased sensitivity to bodily sensations (body aches, tingles, feelings of pain and pleasure, warmth and fatigue) increased heart rate and blood pressure small pupils anxiety and confusion intense visual hallucinations dissociation

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