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Patients with HIV infection, with hepatitis B or C virus, and those with cirrhosis are at increased risk from antiretroviral therapy and decompensation by toxic drugs

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10,193,194 iNAMPT localizes to the cytoplasm, nucleus and mitochondria, and NAMPT has also been found to be upregulated in several solid human tumors, including the colon cancer, 7 glioma 8,9 and breast, 195 prostate, 196 thyroid, 197 and gastric 198 carcinomas

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