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ZnT10, though classically assigned to Golgi and endosomal compartments, can also traffic to the plasma membrane under specific conditions, such as high extracellular zinc or altered manganese levels, possessing a dynamic role in metal detoxification 32

doi: 10.1177/1753425908099170 39 GarlandaCDinarelloCAMantovaniA

Tanaka et al., 2010), followed by PINK1-mediated phosphorylation of these ubiquitinated substrates to amplify polyubiquitin chain signaling (Harper et al., 2018)