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doi: 10.3390/su151511906 22

Sphingolipid metabolites, such as sphingosine 1-phosphate, play a crucial role in the modulation of inflammatory diseases (5764) as well as in regulating inflammation and neurodegeneration in EAE (56)

It is also endogenous, meaning it is always in our bodies, and is naturally found in most cells

BMC Med Genomics 5:32 Kongpan T, Mahasirimongkol S, Konyoung P, Kanjanawart S, Chumworathayi P, Wichukchinda N, Kidkeukarun R, Preechakul S, Khunarkornsiri U, Bamrungram W et al (2015) Candidate HLA genes for prediction of co-trimoxazole-induced severe cutaneous reactions