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Data availability: Data from the pregnancy study is available at the European Nucleotide Archive (ENA) under project PRJEB38528, Placenta biopsies, saliva samples, vaginal and rectal swabs collected at delivery for babies at term, and samples and the non-pregnant participants samples are under project PRJEB37731, Effects of the menstrual cycle and hormonal contraceptives on the human microbiome , samples SAMEA6662389SAMEA6662857

After that, smoking rates dropped to between 20% and 29% for more than two decades