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Solutions: Use a higher concentration with smaller reconstitution volume, which does not actually solve the stability issue since the same amount of time passes Start at a higher dose point if your protocol allows (only if you have already titrated up with a smaller vial) Consider aliquoting into smaller sterile vials and freezing portions for later use (reduces contamination risk to the main vial) Share the reconstitution timing with your dosing schedule, only reconstituting when you are at a dose where you will use the vial within 28-60 days For researchers at 10 mg or 15 mg weekly, the 60 mg vial is perfect

The tirzepatide vs semaglutide dosage comparison shows tirzepatide outperforms semaglutide by 5-7 percentage points in weight loss

Telomere length and biological aging Cawthon RM et al

The average absorption rate of a oral supplement is only 45 % compared with 90% via an IM shot