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They may include: The type of opioid The amount of drug taken How it is taken (injecting or snorting) How your body processes it Individual health factors like age, weight, hydration, and metabolism affect how long opioids can be detected

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Similarly, earlier studies led by Sikiric and colleagues in the 1990s suggested safety and benefit in gastrointestinal conditions such as ulcerative colitis, but these reports were published only in abstracts or local conference proceedings, with no independent replication or peer-reviewed validation