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This will allow us to determine the correlation of the in vitro results with the actual in vivo responses

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It is postulated that viral infection could trigger CD8 T-cell hyperactivation and increased antibody production to compensate for this deficient CD4 T-cell response in genetically predisposed individuals (HLA-DR15), which may lead to autoimmune hypophysitis or direct pituitary damage

The findings aim to provide actionable insights for policymakers, clinicians, researchers and patients to advance DHT-driven, patient-centric approaches, ultimately improving patient outcomes and addressing the unmet medical needs of rare disease populations worldwide, ensuring they have equitable access to innovative treatments and improved healthcare