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These effects were noted in obese mice and beta(3)-adrenergic receptor knock-out mice, suggesting that AOD-9604s actions are not mediated directly through the beta(3)-adrenergic receptor, a known facilitator of lipolysis

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Immediately following the injections, you may experience: Minor redness generally lasts no longer than 1 hour, and for most patients, this dissipates before they leave the office (15 minutes) Swelling generally increases for the first 24 hours, before resolving within 48-72 hours

This means concerns about long-term IGF-1 elevation do not apply to AOD 9604