bioavailability of oral glutathione standard poor Reasons for poor oral bioavailability poorly water soluble drugs bioavailability of glutathione oral poor

Perovic, D., Gojkovic, S., Jelic, M., et al

Liver Physiol

FIGURE 7 The strong role of severe oxidative stress, reduced antioxidant defenses like GSH with increased lipid peroxidation and malondialdehyde generation (213), lipid, protein and DNA oxidation with increased apoptosis and necrosis in atherosclerosis as a major cause of cardiovascular diseases and stroke, supports the use of complementary and alternative medicines, dietary supplements, and antioxidants with hardly any adverse effect, able to restore homeostasis reversing oxidative stress (214)

How to interpret the labs Topical and systemic exposure contexts should not be treated the same