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297,298 Additionally, two other key trials of SGLT-is in people with CKD showed that canagliflozin reduced the primary composite outcome of ESRD (dialysis, transplantation, or a sustained estimated eGFR 45 ml/min/1.73m 2 and a urinary-to-creatinine ratio (uACR) 25 mg/mmol or 2045 ml/min/1.73 m 2 or established CVD are recommended for diabetic patients because of its high glucose-lowering efficacy and proven cardiorenal benefits

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More clinical trials of MO should be applied when the safety of MO has been confirmed

How to Read This Report This report is prepared using the most recent information posted in the FDA's Enforcement Reports Database (for recalls), Warning Letters Database (for warning letters), and Drug Imports Alerts Database (for drug importers subject to import bans)