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Azcue et al propose that fatigue could be due to autonomic nervous system involvement

\n\n\n\n These findings have generated genuine scientific interest in BPC-157 as a potential candidate for further development in IBD research, though the absence of human clinical trials means that clinical applicability remains to be established

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Summary: Adults with B12 deficiency and nerve pain typically require 1 mg hydroxocobalamin injections intramuscularly on alternate days until symptoms improve, followed by maintenance injections every two months