In a frequently cited 2003 study published in the Bulletin of Experimental Biology and Medicine, Khavinson and colleagues reported that EpitalON induced telomerase activity and telomere elongation in human somatic cells cultured in vitro
6.5.3 Extremely limited clinical intervention Most current evidence derives from preclinical models, while interventional clinical trials specifically designed to target the ferroptosis pathway in AD patients remain scarce
BPC-157 is a synthetic pentadecapeptide studied in preclinical research for tissue-repair signaling, inflammation-pathway modulation, and gastrointestinal cytoprotective mechanisms
10.1016/j.phymed.2024.155813 Summary Keywords renal fibrosis, epithelial-mesenchymal transition, natural products, traditional Chinese medicine, inflammation, oxidative stress, TGF- Citation Zhao Q, Jin M, Zhao Q, Wang Z, Zhao C, Xue X, Qiao X, Qu P, Han D and Tao R (2025) Natural products in traditional Chinese medicine for renal fibrosis: a comprehensive review