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It was suggested that the expression of the pro-inflammatory cytokines and chemokines, including IL6, IL1, and TNF, are due to activated NFB transfers to the nucleus of the liver cell and binds to their DNA

With IV infusion therapy, treatment is usually less frequent: most patients come in one to two times per week over a series of weeks

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Genotyping was carried out using a multiplex PCR protocol for the detection of GSTT1 null genotypes and an internal amplification control (Albumin gene ALB)